Our Research Published in “Investigative Ophthalmology & Visual Science”
The research conducted by Jue Shi (PhD student), Shinichi Ikeda (Project Assistant Professor), and Tomokazu Fukuchi (Project Instructor) et al. has been published in Investigative Ophthalmology & Visual Science.
This study demonstrates, through genetic and pharmacological approaches, that mast cells showing distinct localization in the choroid undergo degranulation in response to myopia-inducing stimuli, leading to choroidal thinning and contributing to the onset of myopia. It marks the first step in our laboratory’s research on choroidal immunology.
[Title]
Choroidal Mast Cells and Their Degranulation Are a Pivotal Trigger for Myopia Development
[Authors]
Shi J, Ikeda SI, Fukuchi T, Chen J, Gettinge K, Imanishi S, Negishi K, Tsubota K, Kurihara T
[Journal]
Invest Ophthalmol Vis Sci. November 2025, Vol.66, 22.
Read the full article here:
Choroidal Mast Cells and Their Degranulation Are a Pivotal Trigger for Myopia Development | IOVS | ARVO Journals
© 2025 Shi J. et al. Published in Invest Ophthalmol Vis Sci. Licensed under CC BY-NC-ND.