Full-time
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Associate Professor / Principal Investigator (PI) Toshihide KURIHARA
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BiographyToshihide Kurihara received his M.D. degree from the Faculty of Medicine, University of Tsukuba, Ibaraki, Japan in 2001. He completed his ophthalmology residency at Keio University Hospital in 2005, and obtained his Ph.D. degree under the supervision of Professor Kazuo Tsubota from Keio University Graduate School of Medicine in 2009. Dr. Kurihara completed his postdoctoral training under the mentorship of Professor Martin Friedlander at the Scripps Research Institute in La Jolla, California, USA. His research interests include hypoxia responses in development, physiology, and pathophysiology of the retina. Currently, he also conducts research focusing on visual restoration utilizing optogenetics technology and molecular mechanisms of myopia development and progression.
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Research KeywordsHypoxia responses, myopia biology, and optogenetic visual restoration
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Links
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Brief Message (free text)I hope to convey the “surprise” that brings us closer to the fundamental nature of science, the “excitement” that advances medicine and ophthalmology itself, and the “fulfillment” of engaging with and contributing to patients.
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Assistant Professor Hidemasa TORII
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Biography
2004 M.D., Keio University School of Medicine
Junior residency, Yokohama Municipal Citizen's Hospital2006 Residency in Ophthalmology, Keio University School of Medicine 2007 Keiyu Hospital 2009 Instructor, Department of Ophthalmology, Keio University School of Medicine 2022 Part-Time Lecturer (concurrent post), Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University 2020-present Assistant Professor, Department of Ophthalmology, Keio University School of Medicine -
Research KeywordsMyopia, Cataract, lens
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Assistant Professor Norimitsu BAN
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Assistant Professor Yohei TOMITA
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BiographyDr. Tomita graduated from Shimane University and completed his ophthalmology residency and retinal fellowship at Keio University School of Medicine, where he also earned his Ph.D. He subsequently joined Harvard Medical School as a Senior Staff Scientist at Boston Children's Hospital.
His achievements include the Young Investigator Awards from the Japan Society of Diabetes Complications (2022), the Japanese Ophthalmological Society (2021), and the Keio University School of Medicine Alumni Association (2021), as well as the Bert M. Glaser Award for Innovative Research in Retina (2021), the Fukuda Award from the Japanese Society of Ophthalmic Diabetology (2024), and the Medical Research Encouragement Prize from the Japan Medical Association (2024). -
Research KeywordsDiabetic Retinopathy, Age-related Macular Degeneration, Retinitis Pigmentosa, Pathological Myopia, Retinopathy of Prematurity
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Links
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Brief Message (free text)I strive as both a clinician and a researcher to pursue patient-oriented research and develop innovative therapies that benefit future generations.
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Assistant Professor Hiromitsu KUNIMI
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Project Assistant Professor Tetsu YOSHIDA
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Research KeywordsNon-visual opsin, neural circuit
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Links
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Contacttyoshida@keio.jp
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Project Assistant Professor Shin-ichi IKEDA
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Biography
- Hakodate-Higashi high school
- University of Tsukuba (B.S. to Ph.D.)
- Juntendo University (as a poslioctoral fellow)
- The University of Tokyo (as an assistant professor)
- Keio University School of Medicine (as an assistant professor)
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Research KeywordsMyopia biology, choroidal immunology, cell biology, myopia, high myopia, pathological myopia,endoplasmic reticulum, unfolded protein response, autophagy, hypoxia response, extracellular matrix,microenvironment, biology of stiffness, sclera, suprachoroidal space, choroid, retinal pigment epithelium,macrophages, mast cells, T cells, B cells, gut microbiome, lactobacilli, lactoferrin, omics
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LinksResearchmap: https://researchmap.jp/ikeshin777
ResearchGate: https://www.researchgate.net/profile/Shin-Ichi-Ikeda-2
Facebook: https://www.facebook.com/share/16FNdPQu8V -
Contact Informationshin-ikeda at keio.jp
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Brief MessageRather than climbing the popular mountains (research fields) that everyone else is climbing, I think it would be a good way to build my identity as a researcher to find mountains that not many people climb but are extremely fun to climb, or that are actually very high.
There are likely to be many wonderful views on the path to the pinnacle of my new mountain,"Myopia Biology" . I am always looking for people who can enjoy looking at these views with us!
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Project Assistant Professor Satoshi IMANISHI
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Research KeywordsChoroid, Vascular biology, Regeneration
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Project Assistant Professor Erisa YOTSUKURA
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Project Assistant Professor Yusaku KATADA
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Biography
2010 Graduated from Keio University School of Medicine 2019 Completed Doctoral Program at Keio University Graduate School of Medicine -
Research KeywordsVisual restoration, Optogenetics
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Links
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Brief Message (free text)Let's pioneer the future of visual restoration!
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Project Assistant Professor Ari SHINOJIMA
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Project Assistant Professor Akiko SUGA
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Research KeywordsVisual function, Optogenetic tools, Inherited retinal diseases
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Links
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Contactasuga01@keio.jp
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Instructor Xiaoyan JIANG
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Project Instructor Ziyan MA
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Biography
- Doctor’s degree, Keio University (Ophthalmology) 2024. Exploring the relationship between vision and the brain through basic medical research.
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Research KeywordsMyopia, Autonomic nervous system, Choroid
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LinksORCiD : 0000-0002-0630-6831
https://orcid.org/0000-0002-0630-6831
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Project Instructor Junhan CHEN
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Biography
2020.04 - 2024.03 Keio University Graduate School of Medicine, PhD course 2024.05 - now Keio University School of Medicine, Department of Ophthalmology, Project Instructor -
Research KeywordsMyopia, Pathologic Myopia, RPE, Digital Health
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Contactchenjunhan@keio.jp
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Brief Message (free text)Clearer vision, brighter future
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Project Instructor Tomokazu FUKUCHI
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Biography
2024.10 - Present Project Assistant Professor, School of Medicine Department of Ophthalmology, Keio University 2024.4 - 2024.9 Researcher, School of Medicine Department of Ophthalmology, Keio University 2023.6 - 2024.3 Postdoc, Department of Molecular Pathophysiology, Institute for Advanced Medical Sciences, Nippon Medical School 2020.11 - 2022.3 Researcher, Faculty of Science Department of Biological Science, Shizuoka University -
Research KeywordsMyopia, Choroid, Immunology, Mast cells, Vasculature, Development, Regeneration, Bioinformatics, Big data, AI, Medical image analysis
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Links
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Contacttomokazu-fukuchi at keio.jp
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Brief Message (free text)With the rapid advancement of big data and omics analysis, new discoveries are being made every day in the field of biomedical science. I believe that being at the forefront of this dynamic change is a unique privilege given to researchers of our time. With respect for the knowledge passed down from the past, I hope to contribute—step by step—toward connecting it to the future.
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Project Instructor Jing HOU
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Biography
2020 - 2024 Keio University Graduate School of Medicine Ophthalmology Doctoral Program -
Research KeywordsMyopia, Choroid, Immune cell, Macrophage, Anti-inflammatory, Oxidative stress
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Links
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Brief Message (free text)We don’t find light by escaping darkness, but by becoming fireflies in it.
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Project Researcher Kanae KUROSAKI
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Project Researcher Ryoko SHIOJIRI
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Project Researcher Shiori YAMAMOTO
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Project Researcher Konomi FUKUDA
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Research KeywordsLowvision
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Project Researcher Hidenori WATANABE
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連絡先hidenoriwatanabe@keio.jp
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Project Researcher Rika TANAKA
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Biography
2019 Bachelor of Applied Biochemistry, School of Engineering, Tokai University 2021 Master of Science in Medical Science, Graduate School of Medicine, Tokai University 2025 Doctor of Philosophy (Ph.D.) in Advanced Medical Science, Graduate School of Medicine, Tokai University Tanaka R.et al., Adherent-invasive E. coli-induced specific IgA limits pathobiont localization to the epithelial niche in the gut. Frontiers in Microbiology, 14: 1031997, 2023.
Tanaka R.et al., Cyclic-di-AMP confers an invasive phenotype on Escherichia coli through elongation of flagellin filaments. Gut Pathogens, 16: 6, 2024.
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Research KeywordsMyopia, Gut microbiota
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Links
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Contacttanaka_rika@keio.jp
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Staff Member Rei SATO
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Staff Member Sami YAMAMOTO
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Staff Member Kaito SERIZAWA
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Staff Member Maki UEDA
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Staff Member Chiaki IKEDA
Part-time
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Project Associate Professor Kazushige TSUNODA
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Project Assistant Professor Atsuro UCHIDA
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Project Assistant Professor Kiwako MORI
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Project Assistant Professor Kaoru FUJINAMI
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Project Instructor Yukihiro MIWA
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Project Instructor Naho SERIZAWA
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Project Instructor Deokho LEE
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Project Instructor Ayaka NAKAI
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Visiting Assistant Professor Xiao HAN
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Biography
EDUCATION
2005 - 2010 Clinical Medicine, Bethune College of Medicine, Jilin University, Bachelor's degree. 2010 - 2012 Ophthalmology, the Second Hospital of Jilin University, Master's degree. 2012 - 2015 Ophthalmology, the Fourth Affiliated Hospital of China Medical University, Doctor's degree. 2023.6 - 2023.12 Ophthalmology, Peking University Third Hospital, Clinical Advanced-Study. Present Ophthalmology, Keio University, visiting scholar CAREERS
2015 - 2020 Ophthalmology, the Fourth Affiliated Hospital of China Medical University, lecturer and attending physician 2020 - Present Ophthalmology, the Fourth Affiliated Hospital of China Medical University, associate professor, associate chief physician and master's supervisor -
Research KeywordsRetinal basic and clinical research
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LinksORCiD 0000-0003 - 2517-9636
https://orcid.org/0000-0003-2517-9636 -
Contacthanxiao106@keio.jp
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Visiting Instructor Jian GUAN
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Biography
- Position in China: attending physician and lecturer
- Job in China:
- The Ophthalmology Department of the First Hospital of China Medical University.
2024.6 - Present A Visiting Instructor in Keio University School of Medicine. -
Research KeywordsRetinitis Pigmentosa, metabolism
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LinksORCiD:0009-0005-7750-9803
https://orcid.org/0009-0005-7750-9803 -
Contactguanjian@keio.jp
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Visiting Researcher (JSPS) Joanna SWIERKOWSKA-JANC
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BiographyI graduated Biotechnology at the University of Life Sciences in Poznan, Poland. During studies I completed scientific internships at the Inland Norway University of Applied Sciences in Norway and the Institute of Molecular Genetics of Montpellier in France. In 2014, I started a PhD programme at the Institute of Human Genetics of the Polish Academy of Sciences (PAS) in Poznan, Poland. In 2020, I defended with honours my PhD dissertation titled ‘Characterization of chosen (epi)-genetic aspects in high myopia in Polish patients’. Later, I received a grant to conduct my own research project titled ‘The role of DNA methylation in etiology of high myopia in Polish children’ at the Institute of Human Genetics PAS. Funded by the European Molecular Biology Organization (EMBO) I completed a research stay at Erasmus Medical Center in Rotterdam in the Netherlands.
Currently, I am doing a postdoctoral training at the Department of Ophthalmology, Keio University School of Medicine in Tokyo, Japan as I received JSPS Postdoctoral Fellowship for Research in Japan. My scientific interest is focused mainly on genetic and epigenetic aspects in myopia and high myopia pathogenesis. -
Research KeywordsMyopia, high myopia, genetics, epigenetics
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Links
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Contactj.swierkowska-janc@keio.jp
joanna.swierkowska@igcz.poznan.pl
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Visiting Researcher Nana KITAMURA
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Researcher Kohei SONE
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Researcher Hikaru MIYAZAKI
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Researcher Akiko KAMIYA
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Researcher Koji YOSHIDA
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Researcher Yuuki YANAGISAWA
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BiographyReceived my Ph.D. in Synthetic Organic Chemistry from Nara Institute of Science and Technology (NAIST) in 2014. With experience at both a Japan-based biotech startup and a global pharmaceutical company, currently engaged in AAV vector production at Restore Vision Inc., taking the lead on overall process development.
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Research KeywordsAAV Vector Production、Formulation Development、Pharmaceutical Analysis、Quality Control、Good Manufacturing Practice (GMP) Regulations、Chemistry, Manufacturing and Controls (CMC) Regulatory Affairs
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Contactyuuki.yanagisawa@keio.jp
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Researcher Momo FUJII
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Researcher Hiroko NIWANO
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Researcher Priscilla Sayami AKAMINE
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Researcher Atsuki HIRAMOTO
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Researcher Masanori KANAI
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Researcher Tomoko YAMAGUCHI
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Researcher Hanako KIYONO
Student
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PhD student Yajing YANG
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BiographyAfter more than a decade of clinical experience in ophthalmology, especially in strabismus and refractive error management, now pursuing Ph.D. research at Keio University on the retinal mechanisms underlying myopia progression.
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BiographyMyopia, retinal function
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Links
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Contactyajing@keio.jp
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Brief Message (free text)I am currently investigating the retinal mechanisms underlying myopia. I hope to contribute to translational approaches bridging clinical ophthalmology and experimental research.
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PhD student Jue SHI
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Biography
2022~ Department of Ophthalmology, Keio University. -
BiographyImmune and myopia
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Contactshijue@keio.jp
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Brief Message (free text)Always maintain a spirit of self-improvement and continue to take on challenges.
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PhD student Xiao FENG
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PhD student Kate GETTINGER
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BiographyKate Gettinger is an optometrist from America with a specialty in low vision and geriatrics. She received her bachelor’s degree in biology from Truman State University, her master’s degree in public health from Washington University in St. Louis, and her Doctor of Optometry from the University of Missouri St. Louis. Her research involves both clinical and basic research. Clinically, she is interested in the epidemiology of ocular diseases and the relationship to quality of life, as well as improving treatment outcomes to reduce the burden of visual impairment. Her basic research includes the study of the mechanisms of diabetic retinopathy, as well as exploring non-visual opsins and the role of various signaling proteins within the eye.
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BiographyDiabetic retinopathy, non-visual opsins, myopia, presbyopia, cataract
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Links
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Contactgettingerk@keio.jp
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PhD student Yuanling ZHANG
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Biography
2014 - 2019 China Medical University Bachelor 2019 - 2022 China Medical University Master 2023 - present Keio University PhD -
BiographyHIF(低酸素誘導因子), CNV(脈絡新生血管)
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Contactzhangyuanling2009@keio.jp
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PhD student Yusuke SHIMIZU
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Biography
September 2021 Department of Ophthalmology, Keio University September 2023 Department of Ophthalmology, National Hospital Organization Saitama Hospital April 2024 Enrolled in Doctoral Program (PhD) September 2025 Scheduled to resign from National Hospital Organization Saitama Hospital -
Research KeywordsRetina / Choroid / Myopia / Defocus / Retinal ganglion cell / Bipolar cell / Melanopsin
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Links
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Contact Informationy.shimizu.md@keio.jp
y.shimizu.keio-med@keio.jp -
Brief MessageI am working on elucidating the pathophysiology of myopia progression and the mechanisms of defocus detection at the retinal level.
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PhD student Yinuo HUANG
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BiographyGraduated with a Bachelor's and Master's degree from Sun Yat-sen University (Zhongshan Ophthalmic Center), an ophthalmologist(China).
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Research Keywords]Myopia, Choroid Blood Flow, Sympathetic nerve system
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PhD student Moran LI
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Biography
- North Sichuan Medical University Bachelor of Medicine
- Xiamen University Master of Ophthalmology
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Research KeywordsVisual restoration, Gene therapy, Retinitis pigmentosa
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Contactlimoran@keio.jp
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PhD student Yuzhu ZHANG
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BiographyI studied at Zhengzhou University from 2015 to 2020 and obtained a bachelor's degree in Clinical Medicine. From 2021 to 2024, I studied at Shanghai Jiao Tong University and obtained a master's degree in Ophthalmology. In 2025, I began studying at Keio University, pursuing a doctoral degree in Ophthalmology.
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Research KeywordsMyopia, Diabetic Retinopathy
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Links
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Contactyuzhuzhang0914@gmail.com
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Brief Message (free text)As an ophthalmologist in China, I completed a three-year standardized residency training program. After that, I came to Japan to engage in basic research related to myopia.
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Medical student Kei KURIMOTO
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Medical student Risa HOSAKA
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Medical student Eijirou SAITOU